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Experimental Canine Tumor Vaccine Tested

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The Yale School of Medicine and The Veterinary Cancer Center in Norwalk, Connecticut, are working together to test and evaluate a cancer vaccine for dogs with certain types of cancerous tumors. If the clinical trial is successful, researchers believe the vaccine will change the way cancer treatment is delivered to animals and people. The Veterinary Cancer Center is accepting dogs for the study.

The EGFT/HER2 Tumor Vaccine is the culmination of years of work by cancer researchers at Yale University. This stage of the project will determine whether or not anti-tumor antibodies are produced in vaccinated dogs. The vaccine ingredients are combined with a patient’s own white blood cells and then injected into a dog at two different intervals during the study. Blood samples are taken at the time of the first injection, then again on day 21, day 28 and day 56.

Yale researchers found that in a laboratory setting, the white blood cells worked with the vaccine to target malignant tumors and start to kill, reducing their size.

One patient in the clinical trial is a Pit bull mix named Valo. His owner reported the dog hasn’t experienced any side effects from the vaccine and is doing all of the regular activities he enjoys.

The ultimate goal of the vaccine study is to develop a new technology for treating cancer in people, as well as animals. This goal is somewhat rare because the majority of clinical trials for pets do not produce the same results when they are tested on people, but the Yale researchers are optimistic this study will benefit all of us.

Here are the eligibility requirements for dogs to enter the study:

  • Dogs must have confirmed mammary cancer or osteosarcoma.
  • Dogs with other types of cancer may be eligible depending on enrollment opening.
  • Dogs must weigh more than 6 pounds.
  • Dogs must not have been on prior steroid use. (ie: prednisone)

For more information about the EGFR/HER2 Canine Tumor Vaccine clinical trial, contact Gillian Rothchild at: Gillian@VCCHope.com.

Story reposted from:
https://www.toegrips.com/canine-tumor-vaccine/
By Sharon Seltzer


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